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Initial guesses are slow

Open Jhsmit opened this issue 4 years ago • 1 comments

When using weighted averaging

And the result is hard to interpret (and shouldnt be)

Perhaps t50 interpolation should be used by default (and/or improved)

Some testing will be required to see what the influence of the initial guesses is on the final fit result

Jhsmit avatar Oct 18 '21 10:10 Jhsmit

We should do some kind of smoothing instead of the current biexponential fit See for example in HDFlex: https://www.biorxiv.org/content/10.1101/2021.12.09.471740v1

Where Piecewise cubic Hermite interpolation is used

Jhsmit avatar Apr 06 '22 08:04 Jhsmit