mmDS(method = 'dream')

[CHENGHAO-WANG]

Hi,

Thanks for the nice package. I am a bit confused how mmDS(method = 'dream') works. Based on the paper of Dream, it uses linear mixed models for DE analysis of bulk RNA-seq data, while mmDS fits cell-level models to scRNA-seq data. Could you please explain how this function actually works under the hood?

Thank you