conan
conan copied to clipboard
Issue in asymmetric run
Hi. I have a receptor-ligand complex and I'm trying to generate plots to visualize the various types of interactions between the receptor and ligand proteins. The complex has 166 residues in total with residues 1-106 belonging to the receptor and residues 107 to 166 belonging to the ligand. First I ran Conan in the symmetric mode to visualize both the intermolecular and intramolecular interactions. But since I'm interested only in the intermolecular interactions (i.e. between the receptor and the ligand) I used the asymmetric mode by adding the following lines:
START_X 1
NRES_X 60
NTERM_X 107
START_Y 61
NRES_Y 106
NTERM_Y 1
But the two plots show different interactions between the receptor and ligand. This is the output from the symmetric run.
And this is from the asymmetric run. I expected the same interactions from the bottom right part of the symmetric run to show up here. But a lot of new interactions are formed. I'm unable to figure out the issue. Please help.