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Issue in asymmetric run

Open accibio opened this issue 1 year ago • 3 comments

Hi. I have a receptor-ligand complex and I'm trying to generate plots to visualize the various types of interactions between the receptor and ligand proteins. The complex has 166 residues in total with residues 1-106 belonging to the receptor and residues 107 to 166 belonging to the ligand. First I ran Conan in the symmetric mode to visualize both the intermolecular and intramolecular interactions. But since I'm interested only in the intermolecular interactions (i.e. between the receptor and the ligand) I used the asymmetric mode by adding the following lines:

START_X 1 NRES_X 60 NTERM_X 107 START_Y 61 NRES_Y 106 NTERM_Y 1

But the two plots show different interactions between the receptor and ligand. This is the output from the symmetric run.

interaction_types

And this is from the asymmetric run. I expected the same interactions from the bottom right part of the symmetric run to show up here. But a lot of new interactions are formed. I'm unable to figure out the issue. Please help.

interaction_types

accibio avatar Feb 16 '24 14:02 accibio