ArchR
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Suggestion in .createGroupBW
Dear ArchR developers, While trying to integrate the createGroupBW in Signac I realized that I think there is a small mistake in: https://github.com/GreenleafLab/ArchR/blame/d9e741c980c7c64e5348c97a74d146cc95f8ba76/R/GroupExport.R#L340 I think it should be:
i = c(trunc(x = (start(x = fragik) - 1) / tileSize),
trunc(x = (end(x = fragik) - 1) / tileSize)) + 1,
Because if the end (or start) position of a fragment is 100 and your tileSize is 100, you would like to assign it to the first bin. Currently 100/100 + 1 assign it to the second bin.
Hi @lldelisle! Thanks for using ArchR! Lately, it has been very challenging for me to keep up with maintenance of this package and all of my other responsibilities as a PI. I have not been responding to issue posts and I have not been pushing updates to the software. We are actively searching to hire a computational biologist to continue to develop and maintain ArchR and related tools. If you know someone who might be a good fit, please let us know! In the meantime, your issue will likely go without a reply. Most issues with ArchR right not relate to compatibility. Try reverting to R 4.1 and Bioconductor 3.15. Newer versions of Seurat and Matrix also are causing issues. Sorry for not being able to provide active support for this package at this time.