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Add transcription factor track to demo instances

Open cmdcolin opened this issue 3 years ago • 2 comments
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Can use 2022 jaspar binding site dataset

http://hgdownload.soe.ucsc.edu/gbdb/hg38/jaspar/ https://genome.ucsc.edu/cgi-bin/hgTrackUi?db=hg38&g=jaspar https://jaspar.genereg.net/about/

It may be useful to have a specialized track type or track config to display it usefully

without extra config, pretty much everywhere on the genome has many binding sites

Screenshot from 2022-01-07 11-33-03

cmdcolin avatar Jan 07 '22 18:01 cmdcolin

could also be worth adding a visualization of long-range interactions with the arc view (we talk about our ability to do this often but a good demo with arc view would be great)

data from ncbi https://twitter.com/NCBI/status/1483865345609904133/photo/1

example file that can use arc view https://ftp.ncbi.nlm.nih.gov/refseq/FunctionalElements/trackhub/data/human/AR109.20201120/FEfeats_AR109.20201120.bb

cmdcolin avatar Jan 19 '22 19:01 cmdcolin

some recent work on a configurable filter added a score>400 filter which is how the JASPAR track is displayed by default on the UCSC website https://jbrowse.org/code/jb2/filter_branch/?config=https%3A%2F%2Fs3.amazonaws.com%2Fjbrowse.org%2Fdemos%2Fucsc%2Fconfig.json&session=share-S5GE4I2L5l&password=0QmC1

cmdcolin avatar May 15 '24 20:05 cmdcolin

this was added. i think making an ensemble regulation track will be good as well, as it is much more filtered compared to jaspar where every base of the genome is annotated with something

cmdcolin avatar Mar 13 '25 04:03 cmdcolin

added ensembl regulatory build to config_demo now

cmdcolin avatar Mar 13 '25 04:03 cmdcolin