I just want to quantify the various cell types within T cells, is this feasible?

[M-jk22]

Hi, I'm interested in studying T cells specifically. So, I'd like to use the tool BayesPrism to quantify the various types of T cells within the bulk data, including CD8 T cells, CD4 T cells, NK T cells, and Treg cells.

[tinyi]

Yes. You may simply specify each individual T cell subtype as an individual cell type. It would be a good idea to have 50 or marker genes for each cell type to ensure high signal to noise ratio for the deconvolution and avoid having cell types being too similar to each other.

Best,

Tinyi

On Mon, May 6, 2024 at 3:41 PM Mjk @.***> wrote:

Hi, I'm interested in studying T cells specifically. So, I'd like to use the tool BayesPrism to quantify the various types of T cells within the bulk data, including CD8 T cells, CD4 T cells, NK T cells, and Treg cells.

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