New CIDO terms request

[linikujp]

1. coronavirus genes.
2. terms of the symptoms and signs
3. different level of illness in this NIH treatment guidance https://www.covid19treatmentguidelines.nih.gov/critical-care/

[yongqunh]

Thanks, Asiyah, for your requests!

We have added a few gene names that come with the protein ontology (PR) protein terms. We are working to soon add more gene terms.

I have many accumulated phenotypes (symptoms and signs). We will add soon by extracting related terms from HP.

[linikujp]

New term suggestion: nursing home, long-term care facility

[linikujp]

In general, patients with COVID-19 can be grouped into the following illness categories:

• Asymptomatic or Presymptomatic Infection: Individuals who test positive for SARS-CoV-2 but have no symptoms

• Mild Illness: Individuals who have any of various signs and symptoms (e.g., fever, cough, sore throat, malaise, headache, muscle pain) without shortness of breath, dyspnea, or abnormal imaging

• Moderate Illness: Individuals who have evidence of lower respiratory disease by clinical assessment or imaging and a saturation of oxygen (SpO2) >93% on room air at sea level.

• Severe Illness: Individuals who have respiratory frequency >30 breaths per minute, SpO2 ≤93% on room air at sea level, ratio of arterial partial pressure of oxygen to fraction of inspired oxygen (PaO2/FiO2) <300, or lung infiltrates >50%

• Critical Illness: Individuals who have respiratory failure, septic shock, and/or multiple organ dysfunction

Reference: https://www.covid19treatmentguidelines.nih.gov/overview/management-of-covid-19/

[linikujp]

This request is posted to HPO, and HPO team asks MONDO team to add the terms. https://github.com/obophenotype/human-phenotype-ontology/issues/5787 https://github.com/monarch-initiative/mondo/issues/1590

[linikujp]

COVID-19 illness related terms have added into MONDO. It will be available upon next release.