postburst_min_values (and interburst_min_values) - don't work as expected - fast AHP after last spike in burst reported instead of slow AHP.

[PolinaL]

Both postburst_min_values and _interburst_min_values seem to measure the fast AHP right after last spike, and not the slow AHP between bursts, as expected. Please see attached trace (model in purple, experimental data in color) - postburst_min_values exp. data extracted value is "mean": -78.15430187470984, "original_std": 2.88731485936629, model value is -78.60786914391257. Thanks.

[PolinaL]

time and voltage data for both model and experimental traces time_and_voltage.zip

[arnaudon]

Here is a zoom, they appear on top of each other, but the red one should be at around -60 instead of at the fast AHP. I think it's because the fast AHP is lower than the slow one, but @PolinaL would like to eventually capture both, so she could control which one is lower

[arnaudon]

I suppose it should be a shift around here: https://github.com/BlueBrain/eFEL/blob/master/efel/cppcore/LibV5.cpp#L3881 but I don't understand cpp and this code enough to try to do it unfortunately...

[arnaudon]

@PolinaL , try this: https://github.com/BlueBrain/eFEL/pull/283 , it solves it for the trace you shared:

[AurelienJaquier]

Hi! I did a c++ implementation that solves your problem in PR #289

With it, we have two new features: postburst_slow_ahp_values and time_to_postburst_slow_ahp

The features start searching for the minimum at a given number of ms after the spike, in order to skip the fast ahp. The number of ms to skip is given by the setting sahp_start and is 5 ms by default.

For your trace @PolinaL 5 ms is not enough, but it works if we increase it to 10 ms with the following command before calling efel:

efel.setDoubleSetting('sahp_start', 10.)

[AurelienJaquier]

Hi @PolinaL ! Did the new features in PR #289 solve your problem? If so, I will merge the PR and close this issue

[AurelienJaquier]

I'll close this issue since the related PR has been merged

[AurelienJaquier]

I'll also close the postburst-slow-ahp branch. You can use the master branch now, it contains all the post-burst features