metage2metabo
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A better focus on the host metabolism when a host is provided
Currently, providing a host will not impact the first part of m2m which is the calculation of individual scopes for bacterial members of the community.
We want the host to be considered with each individual symbiont already at that step. This would lead to calculating what is producible by the symbiont in a community consisting of the host + the symbiont. More precisely, the activated metabolism of the host in the medium will provide new metabolites that can be used by the symbiont. Using miscoto focus
should do the job.
The community scope will be calculated as it is currently, considering the added value of the host metabolism as well as the other symbionts' metabolism.
A specific focus on the host gain with its community (what it produces with the community - what it produces alone) should be performed too.
Should the targets to be considered be the host metabolites that are producible only in community?