Arthur Rand

Hello @Machadum, Sorry about the delayed response. A couple things I may adjust: 1. I usually use a p-value of 0.01 (the default in the segmenter), but [others](https://github.com/nanoporetech/modkit/issues/367) have found...

@Sellerzzz Could you tell me the error message? I'd like to make it easier to understand if possible.

@Machadum, > Thank you for your answer. For effect sizes > 30%, is it better to run dmr pair on single sites without any filter and then filter out column...

Hello @irc47 Let me find out for you.

Hello @ngamarra, Do you expect that one of the samples will have very few methylated adenine residues? What you could do is determine the values on a sampling of both...

Hello @Ge0rges, You can only do one region at a time with `--region`, I should revise the help string to say "Commas are allowed in the genome coordinates" e.g. "chr20:62,141,748-62,145,077"....

Hello @imilenkovic, Sorry for the major delay is getting back to you. > Is the filtering done based on the same modification probability value which is used to differentiate between...

Hello @angelluigi, To make things a little easier, could you tell me the output of `modkit --version` and show me the exact commands you're running? For `modkit motif` do you...

Hello @gsukrit, Sorry for the delay in getting back to you. Could you tell me which version of Dorado and the base modification models you're using (for R9 and R10)?...

Hello @gsukrit, Ok. I was initially concerned that potentially the R9 modification calls had an older version of the modification tags that can be misinterpreted - but what you have...