Arthur Rand

Results 603 comments of Arthur Rand

Hello @angelluigi, In general, there is no disadvantage to increasing coverage. However, beyond 200x is _probably_ not necessary unless you think there are rare sub-populations in your data (again it...

Hello @ADHDrian, This has been a long-standing [limitation](https://nanoporetech.github.io/modkit/limitations.html) but is easy enough to remove. I'll look into getting it into the next release. What caller is producing `MM:Z:N-21891` tags?

Hello @KunFang93, I can get this to you soon, it's on the roadmap.

@KunFang93 Any chance you'd be willing to send me that fill SAM record so I can use it for testing? I can make one up, but better yet to test...

Hello @KunFang93, I responded via email. Thank you for the sample data. I'll get you a build asap.

Hello @KunFang93, I've sent you an email with some concerns I have regarding the output of DNAscent. Happy to follow up here or over email.

@KunFang93 I'm glad I asked over here then! I've sent you email, let's correspond over there since it involves your data, and we can bring the discussing back public when...

Generic tags are now supported as of [v0.4.3](https://github.com/nanoporetech/modkit/releases/tag/v0.4.3) and later.

Hello @hassebossenbroek, Would you expect there to be _any_ 5hmC in your sample? It is possible that if you don't have any of a specific base modification (5hmC) that the...

Hello @hassebossenbroek, From the reports I've seen, the levels of 5hmC in human samples is somewhere in the range of 1% or less (e.g. [Foox et al.](https://link.springer.com/article/10.1186/s13059-021-02529-2#Sec42)). If you're using...