Alina Tikhova

Results 8 issues of Alina Tikhova

We have freshly implemented Lee-Crippen SMARTS pKa calculation method. Using new datasets from various sources we need to adjust the decision SMARTS-tree, which is an essential part of this method,...

Improvement
Core

We need to implement calculation method for **logD** - a distribution coefficient widely used to measure the **lipophilicity of ionizable compounds**, where the partition is a function of the pH....

Core
Feature

We need to switch the existing Java API exact match method to using molecules and reactions hashes to increase its performance. A similar change was recently implemented in Bingo Elastic....

Core
Indigo API
Feature

Exact search test for Bingo Elastic fails getting less hits than we have in the reference for three particular molecules: q_55 (on the picture) , q_56, q_57. As the search...

Bingo-Elastic

Bingo Exact Search with no flags, which is equal to the `ALL` flag - the most restrictive one, matches the molecules, which are not in fact exactly similar to the...

Bug
Bingo
High priority

build_bingo_postgres_windows_msvc_x86_64 step in ci fails due to the following errors ([link to the failed action](https://github.com/epam/Indigo/runs/6401989922?check_suite_focus=true)): The code can be found in the branch `bingo_ci_pg14_windows` .

Bingo
CI

There isn't any documentation for Bingo setup and related options. Would be convenient to have something like this page for Indigo Toolkit: https://lifescience.opensource.epam.com/indigo/options/index.html

Documentation

**Background** Currently there are no tests covering Bingo Oracle. It's needed to add them and the corresponding step to Indigo CI.

Bingo