Persistent configuration customizations?

[alexitheodore]

Based on the documentation, I cannot tell one way or another whether customizations at the module-level are persistent over sessions/restarts etc. If so - how would I go about restoring things to default?

Ultimately, I'd like to make a centralized configuration file that survives a system restart but adds as little overhead as possible. I am using this as part of a postgres plpythonu procedure, so everything needs to be packaged up nice and neat to fit in - not a normal python dev environment.