Ben Weisburd
Ben Weisburd
To further troubleshoot this, I recomputed scores for cached variants and compared cached scores vs recomputed scores. It turns out this issue of scores changing even though the transcripts/model/parameters didn't...
More stats - this issue of scores changing appears to affect 28% of variants with Pangolin on hg38 5% of variants with Pangolin on hg37 and does not occur for...
Until this is fixed, if you decide you want to double-check some score, you can't just rerun the same variant because the server will just return cached results. However, you...
I'm not yet 100% sure, but updates over the past week have most likely fixed this issue with Pangolin scores.
I've reset the cache this morning, so any previously-computed scores will be recomputed from scratch. Next week I will double-check that the pangolin scores are now stable.
I've confirmed that Pangolin scores are now stable and reproducible as of 1 month ago. Later this week, I will be add a notification about this to the release updates...