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Published 20 hours ago • verified publisher icon apriha

Multisample VCF

Open kkarbasi opened this issue 5 years ago • 1 comments

Merging snps from different samples and saving them as a multi-sample VCF. Hi, would that be possible?

Thanks!

kkarbasi avatar Oct 14 '20 16:10 kkarbasi

Thanks for the issue! Yes, I think a multi-sample VCF could be constructed from merged files. To do this, I'm envisioning the SNPs object maintaining the results of each merge (e.g., RSIDs in common, discrepant SNPs) and building the VCF from that summary information.

Related, the fix for this issue should also operate in reverse to read a multi-sample VCF, identifying discrepant SNPs in the process.

apriha avatar Oct 16 '20 05:10 apriha