Device.Net
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Android Serial Port Access
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Check out the Android Serial Port Access library.
Create a bridge?
Write a new one?
One solution could be to implement USB communication with different serial converter chips/vendors.
usb-serial-for-android java lib supports many vendors and UsbSerialForAndroid is a port to .NET.
With Device.Net and the cross-platform implementation of USB communication, the support of different chips/vendors would be also cross-platform with a single implementation.